MICROBIOME
FOR YOUR HEALTH

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Based on the satisfactory results, researchers began to examine the skin microbiome in detail and found that all individuals who had a skin problem (inflammation, eczema, acne, …) had a higher proportion of harmful microbes compared to those with healthy skin.

microbiome
for your health

the intestinal epithelium
is essentially skin
turned inside out

Everything that happens inside the gut affects the processes on the surface of the skin. The intestinal epithelium maintains contact and communication with intestinal bacteria that influence skin flora. Thousands of different types of bacteria make up our microbiome. The microbiome in our skin, the body’s largest organ, regulates inflammation and serves as a barrier against pathogens. Chronic inflammation, stress, changes in skin pH, and diet can create an imbalance in this microbiome.

different skin microbes
protect the skin in
different ways

One type of bacteria secretes antimicrobial substances that protect us against pathogens, while another uses skin lipids to create short-chain fatty acids to ward off microbial risks. Another type of bacteria secretes lipoteichoic acid (LTA), which serves to prevent the release of inflammatory cytokines so that the skin does not become inflamed(8).
Poor lifestyle and antibacterial hygiene products destroy our microbiome, which is the main cause of all skin problems. A well-functioning microbiome can also protect us from UV radiation. A strain of bacteria that suppresses the development of cancer lives on healthy skin. They produce the substance 6-N-hydroxy-aminopurine (6-HAP), which kills several types of cancer cells, while it is non-toxic to healthy cells(9).

expert opinion

RNDr. Petr Ryšávka, Ph.D.

“Common probiotics are largely destroyed already in the stomach by aggressive digestive juices, bile in the duodenum also has a very devastating effect”(1).
HOW LONG TO USE
NYADERM® PROBIO?
The duration of the NYADERM® ProBio treatment depends on what problems you need to solve with its help.

3

AESTHETIC PROBLEMS

I recommend taking for a minimum of 3 months(1).
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6

HEALTH PROBLEMS

I recommend long-term use for 5-6 months. Probiotics are completely safe and taking them is like eating yogurt(1).
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2

IMMUNE PROBLEMS AND ANTIBIOTIC USE

I recommend taking for a minimum of 1 – 2 months(1).
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STUDIES AND CITATIONS

All studies and citations referenced.
Studies and citations

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The unique combination of ingredients in NYADERM® Anti-aging Drink addresses a broader spectrum of problems.

NYADERM® Probio

is a unique dietary supplement containing an optimised combination of clinically tested 4th generation probiotics, prebiotics, flavobiotics, riboflavin and biotin.

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Studies and citations
1. RNDr. Petr Ryšávka, Ph.D., molecular biologist and probiotics expert
2. PROBIOTIC BIOFILM ON CARRIER SURFACE: A NOVEL PROMISING APPLICATION FOR FOOD INDUSTRY, M. GROSSOVA*, P. RYSAVKA and I. MAROVA, Faculty of Chemistry, Department of Food Chemistry and Biotechnology, Brno University of Technology, Purkynova 118, CZ-61200 Brno. Czech Republic, 2017
3. Manach,C., Scalbert,A., Morand, C. 2004, Polyphenols: Food Sources and Biovailability, American Journal of Cilinical Nutrition, 79(5), 5.2004, s.727-47. Available at: https://academic.oup.com/ajcn/article/79/5/727/4690182
4. Afaq,, F., Katiyar, S.K.2011, Polyphenols: Skin Photoprotection and Inhibition of Photocarcinogenesis. Mini-Reviews in Medicinal Chemistry, 11(14), December 2011, s.1200-1215. Available at: https://www.nebi.nlm.nih.gov/pubmed/22070679.
5. Afaq, F., Zaid, M. A. Khan, N., a kol.2009. Protective Effect of Pomegranate-Derived Products on UVB-Mediated Damage in Human Reconstituted Skin. Experimental Dermatology, 18(6), June 2009, s. 553-61. Available at: https://www.nebi.nlm.nih.gov/pubmed/19320737
6. Source: Antibiotics – WikiSkripta
7. Steven R. Gundry, the Longevity Paradox – How to Die Young at a Ripe Old Age, HarperCollins Publishers, USA, 2019
8. Akst, J.2014 Microbes of the Skin. The Scientist, 13.6.2014
9. University of California – San Diego.2018. Beneficial Skin Bacteria Protect Against Skin center. ScienceDaily
Studies and citations
1. RNDr. Petr Ryšávka, Ph.D., molecular biologist and probiotics expert
2. PROBIOTIC BIOFILM ON CARRIER SURFACE: A NOVEL PROMISING APPLICATION FOR FOOD INDUSTRY, M. GROSSOVA*, P. RYSAVKA and I. MAROVA, Faculty of Chemistry, Department of Food Chemistry and Biotechnology, Brno University of Technology, Purkynova 118, CZ-61200 Brno. Czech Republic, 2017
3. Manach,C., Scalbert,A., Morand, C. 2004, Polyphenols: Food Sources and Biovailability, American Journal of Cilinical Nutrition, 79(5), 5.2004, s.727-47. Available at: https://academic.oup.com/ajcn/article/79/5/727/4690182
4. Afaq,, F., Katiyar, S.K.2011, Polyphenols: Skin Photoprotection and Inhibition of Photocarcinogenesis. Mini-Reviews in Medicinal Chemistry, 11(14), December 2011, s.1200-1215. Available at: https://www.nebi.nlm.nih.gov/pubmed/22070679.
5. Afaq, F., Zaid, M. A. Khan, N., a kol.2009. Protective Effect of Pomegranate-Derived Products on UVB-Mediated Damage in Human Reconstituted Skin. Experimental Dermatology, 18(6), June 2009, s. 553-61. Available at: https://www.nebi.nlm.nih.gov/pubmed/19320737
6. Source: Antibiotics – WikiSkripta
7. Steven R. Gundry, the Longevity Paradox – How to Die Young at a Ripe Old Age, HarperCollins Publishers, USA, 2019
8. Akst, J.2014 Microbes of the Skin. The Scientist, 13.6.2014
9. University of California – San Diego.2018. Beneficial Skin Bacteria Protect Against Skin center. ScienceDaily

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Active ingredients in one capsule: mg /kap. % DRHP*
Bifidobacterium lactis HN019 biofilm Lactobacillus rhamnosus HN001 biofilm 10 x 109 CFU**   –      
Olive, pomegranate, grapefruit, orange, blueberry and green tea extract (polyphenols 51%) 100 mg (of which  epigallocatechin-3-gallate: 6 mg)    –
Riboflavin (vit. B2) 1 mg 71,4%
Biotin (vit. B7) 25 ug 50%
*Reference Daily Intake  **CFU – colony-forming unit at production exit control Ingredients:  Soluble glucose fibre (glucofibre – prebiotic), inulin (prebiotic) , extract from olives, pomegranate, grapefruit, orange, blueberries and green tea (polyphenols 51%), probiotic cultures in the form of biofilm ( Bifidobacterium lactis HN019 biofilm, Lactobacillus rhamnosus HN001 biofilm ), glucomannan (konjac mannan), riboflavin (vitamin B2), biotin (vitamin B7), added substances: filler (hydroxypropyl methylcellulose), anti-caking agent (magnesium salts of fatty acids), mixed component: capsule composition (hydroxypropyl methylcellulose, gellan gum)

3. Uvedená denní sazba je platná v případě zvýhodněného členství v rámci NYADERM BEAUTY CLUB, zvolené varianty časově neomezeného předplatného a odběru minimálně 4 ks NYADERM® Anti-aging Drink během kalendářního roku. Ceny jsou uvedeny včetně DPH (15%) a příslušných poplatků. Neobsahují ale poplatky za doručení (není-li uvedeno jinak).

1. V závislosti na výsledcích klinických studií patentovaných složek obsažených v přípravku NYADERM® Anti-aging Drink v množství odpovídajícím provedeným klinickým studiím.

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